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Home Entertainment

How Selma Blair and Christina Applegate ‘Commiserate’ Over MS

by DigestWire member
April 15, 2026
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How Selma Blair and Christina Applegate ‘Commiserate’ Over MS
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Selma Blair and Christina Applegate’s connection remains strong even 25 years after The Sweetest Thing.

Blair, 53, exclusively told Us the two have also bonded over their respective multiple sclerosis diagnoses over the last few years.

“Right when she finished [Dead to Me], she was actually at my house, the kids were playing, and she was saying she wasn’t well, and I was going, ‘Oh, this reminds me a lot of me … I couldn’t walk, feet swelled up,’” Blair shared, recalling what she said when Applegate, 54, first broached her health issues.

“I said, ‘I think you need to get an MRI,’” Blair continued. “And she’s like, ‘Ugh,’ but she really wasn’t feeling well, and she got an MRI, and it did reveal that she had MS. … So I think we both watched every episode of The Love Boat from our beds, texting each other. There’s things we would kind of commiserate [about], because we both became bed girls for a while, definitely years. So we commiserate and laugh. She definitely was kind of the tough one about MS. She was very ballsy about it. She’s amazing.”

Blair’s bed era, as she lovingly calls it, continues with a new partnership. On Tuesday, April 14, she revealed her collaboration with Kansas City–based lifestyle brand Mersea to create a limited-edition pajama capsule collection, Sea La Vie, that “celebrates sleepwear as a modern self-care ritual.”

Selma Blair in Mersea bed jacket and jumper
Selma Blair in Mersea Robin Harper for MERSEA

“I met this wonderful woman-owned business years ago, when I was really not doing great with MS,” said Blair, who was diagnosed with multiple sclerosis in 2018. “I was in bed a lot, and I got this beautiful care package, and it made such an impression on me, and I obviously enjoyed it so much.”

Selma Blair Is ‘Feeling More Confident’ in Her Hollywood Return

“Bed is something that I’m in a lot,” Blair continued. “So now I have more pajamas than the average bear, and I couldn’t be more thrilled. But I could also throw on my bed jacket and go out and look really, really chic.”

The line includes bed jackets, crisp cotton looks and accessories like hair towels and eye masks — and these days, while the pajama love remains, Blair shared with Us that she’s often feeling a lot better.

“But I think it sometimes could be confusing, because sometimes I’ll have a walking stick and sometimes I don’t need it, or try to go without it,” Blair explained about what people misunderstand about MS. “You don’t realize, sometimes people just don’t have the energy level all day to keep walking, so they need to do that, or might not be safe or my balance isn’t good. I can actually walk fine now, but yet quickly do something I topple over and I can look a bit unhinged, so the stick and the dog and things are good indicators and do help me.”

Selma Blair Shares Health Update Amid Her Multiple Sclerosis Battle

“That is something that I wish people could understand,” she continued. “When someone saw my documentary, a husband actually said, ‘You saved my marriage.’ He’s like, ‘My wife has MS and I always just thought, ‘Oh, you’re good enough to do these things, but then when it’s time for us to have date night, you’re just dead out.’ And it’s like, sometimes things suffer, sometimes we don’t get to have it all when you have limited energy. So for me, fatigue is my big [symptom] with MS, but other people might not have fatigue at all.”

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