The Twisted Tale of Amanda Knox allowed Grace Van Patten to work with sister Anna Van Patten.
Grace, who is Anna’s older sister, grew up with her siblings in New York City before attending Fiorello H. LaGuardia High School. After being directed by her father, Timothy Van Patten, in an episode of The Sopranos, Grace continued to find success with roles in Boardwalk Empire, Maniac and Nine Perfect Strangers.
Grace skyrocketed to fame after being cast as Lucy in Hulu’s Tell Me Lies. She went on to score the lead role as Amanda Knox in a limited series, which will chronicle the period after Knox was wrongfully accused in Meredith Kercher’s murder trial, her time in prison and her journey to freedom. Margaret Qualley was originally set to play Knox in Hulu’s scripted series, but she exited the project and Grace replaced her.
The Twisted Tale of Amanda Knox paved the way for Grace to work with Anna, who plays Knox’s real-life sister.
See How Hulu’s ‘The Twisted Tale of Amanda Knox’ Compares to Meredith Kercher’s Murder Trial
“I’ll say that Grace is f***ing amazing. That’s what I will say,” Knox exclusively told Us Weekly in March 2025. “I’m in a very, very privileged position as someone who is a subject of a story. Typically someone in my position — the subject — doesn’t get to be an executive producer of their own show.”
Keep scrolling for what to know about Anna after she collaborated with Grace on The Twisted Tale of Amanda Knox:
What TV Shows Did Anna Van Patten Work On Before ‘The Twisted Tale of Amanda Knox’?
Anna made appearances on Law & Order: Special Victims Unit, FBI: Most Wanted, Gossip Girl and she has been cast in season 3 of Euphoria.
Who Else Is Part of Grace and Anna’s Famous Family?
Grace and Anna’s father is director and producer Timothy Van Patten and mother is Wendy Rossmeyer Van Patten. Their uncle is comic actor Dick Van Patten and their cousin is actress Talia Balsam, who is the daughter of Joyce Van Patten. Grace and Anna have a younger sister: June.
Hollywood’s Most Memorable Celebrity Siblings Over the Years
What Has Anna Shared About Her Career?
During a joint interview with her mother in January 2025, Anna spoke with Modern Luxury about breaking into the industry.
“I went to a performing arts high school where you could major in a subject. I majored in drama, and then I went to the New School for college where I studied film,” she explained. “I think learning all aspects of film can only teach me more about the art as a whole. I think that having Gossip Girl as my first job is teaching me a lot, because there’s really nothing like learning from being on set.”
Anna continued: “I’m so thankful for that, but I really want to learn to be more hands-on behind the camera. I think this is all teaching me a lot for potential future projects.”
Have Grace and Anna Worked Together Before?
The sisters shared the screen for the first time in Hulu’s The Twisted Tale of Amanda Knox, which premiered in August 2025. Grace played Amanda while Anna Van Patten was cast as her sister, Deanna. The rest of the Knox family was portrayed by Sharon Horgan and John Hoogenakker.
